Treatment

LacriFill Canalicular Gel

Also known as LacriFill, Canalicular Gel, Crosslinked Hyaluronate Gel, Gel Tear Duct Plug, Temporary Tear Drain Occlusion

Updated May 16, 2026For educational purposes only. Not a substitute for medical advice. See our terms.

Bottom Line

LacriFill is a sterile gel placed into the tear drainage channels. It slows tear drainage so more tears stay on the eye surface.

LacriFill is a crosslinked hyaluronate canalicular gel occlusive device for dry eye. It is placed into the canaliculus, which is part of the tear drainage pathway 1.

The goal is similar to punctal plugs: keep more tears on the eye. The product instructions state that it blocks tear drainage by occluding the canalicular system 2.

The same instructions list use for up to 6 months in patients with dry eye symptoms. They also list active infection and known lacrimal outflow obstruction as reasons not to place it 2.

How It Works

Tears normally drain through tiny openings near the inner eyelids, then through small channels into the nose. LacriFill places gel inside those channels.

By slowing drainage, the gel can keep more natural tears and eye drops on the surface. A clinical study evaluated a crosslinked hyaluronate canalicular gel occlusive device for dry eye 1.

Risks and Limits

Possible issues include discomfort, irritation, too much tearing, infection, canaliculitis, punctal narrowing, lid swelling, or vision change. The product instructions say infection, irritation, or bothersome tearing may require removal 2.

It is not for everyone. Active eye or eyelid infection, known tear outflow blockage, and allergy to device materials must be reviewed before placement.

Cost and Insurance

Coverage depends on your dry eye diagnosis, plan rules, and clinic billing. Some plans may require proof that standard drops were not enough.

Ask for the device cost, placement fee, follow-up fee, and removal policy. Also ask whether both eyes are treated on the same day.

Common Questions About LacriFill

No. Both slow tear drainage, but LacriFill is a gel placed inside the canaliculus.

Next Steps

  1. 1Ask your eye doctor to confirm dry eye type and tear drainage patency.
  2. 2Review infection, tearing, allergy, and prior tear duct history before placement.
  3. 3Ask whether both eyes will be treated and what follow-up is planned.
  4. 4Get a written estimate for device, placement, follow-up, and removal costs.
  5. 5Call the clinic for pain, discharge, swelling, severe tearing, or vision change.

Find specialists for LacriFill Canalicular Gel

Board-certified ophthalmologists who treat LacriFill Canalicular Gel.

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